Symposium Co-Chairs: Richard DiMarchi & Ved Srivastava
07:30 am - 09:00 am | Registration and Coffee | Registration Area 4 |
09:00 am - 12:30 pm | SESSION I Session Chair: Ved Srivastava, GlaxoSmithKline |
Grand Cypress |
09:00 am - 09:20 am | Opening Remarks: Steven Smith, Sanford-Burnham Medical Research Institute |
Grand Cypress |
09:20 am - 10:00 am | MD1 Richard Di Marchi, Indiana University Macromolecule Therapeutics in Metabolic Dysfunction |
Grand Cypress |
10:00 am - 10:40 am | MD2 Annette G. Beck-Sickinger, Universitat Leipzig New Approaches to Target Metabolic Diseases by Chemically Modified GPCR Ligands |
Grand Cypress |
10:40 am - 11:15 am | Refreshment Break | Grand Cypress Prefunction |
11:15 am - 11:45 am | MD3 Andrew Young, Phoundry Pharmaceuticals Optimization of Metabolic Peptides |
Grand Cypress |
11:45 am - 12:15 pm | MD4 Laszlo Otvos,, Temple University Adiponectin Receptor Agonist Peptides Restore Normal Metabolic Conditions and Exhibit Anti-fibrotic and Anti-cancer Activities in Vitro and in Vivo |
Grand Cypress |
12:15 pm - 01:30 pm | Lunch - provided | Grand Cypress |
01:30 pm - 04:05 pm | SESSION II Session Chair: Richard DiMarchi, Indiana University |
Grand Cypress |
01:30 pm - 02:15 pm | MD5 Matthias H. Tschöp, Technische Universität München Gut-peptide Based Poly-pharmacy for the Treatment of Obesity and Diabetes |
Grand Cypress |
02:15 pm - 02:45 pm | MD6 Christina Lipscombe, Philadelphia College of Osteopathic Medicine Protein Kinase C beta II (PKC βII) Peptide Inhibitor Exerts Cardioprotective Effects in Myocardial Ischemia/reperfusion Injury |
Grand Cypress |
02:45 pm - 03:00 pm | Refreshment Break | Grand Cypress Prefunction |
03:00 pm - 03:30 pm | MD7 Jung-Mo Ahn, University of Texas at Dallas Application of Stable GLP-1 Analogs as PET Imaging Agents for Non-Invasive Assessment of Pancreatic Beta-Cell Mass |
Grand Cypress |
03:30 pm - 04:00 pm | MD8 Thomas Høeg-Jensen, Novo Nordisk Design of Insulin Degludec and Co-formulations with Insulin Aspart and Liraglutide |
Grand Cypress |
04:00 pm - 04:05 pm | Closing Remarks: Richard Di Marchi, Indiana University |
Grand Cypress |
07:30 am - 06:00 pm | Registration | Registration Area 4 |
01:00 pm - 06:00 pm | Exhibitors/Posters set up | Regency Portico |
06:00 pm - 06:05 pm | OPENING REMARKS: Robin Offord, Mintaka Foundation & President APS |
Grand Cypress |
06:05 pm - 06:15 pm | OPENING REMARKS: Symposium Co-Chairs: Ved Srivastava, GlaxoSmithKline Andrei Yudin, University of Toronto |
Grand Cypress |
06:15 pm - 07:00 pm | Introduction: Andrei Yudin, University of Toronto, APS Co-Chair OPENING LECTURE: L01 Richard Lerner, The Scripps Research Institute Combinatorial Antibody and Peptide Libraries |
Grand Cypress |
07:00 pm - 07:10 pm | Announcements: Student Affairs Committee and Symposium Proceedings |
Grand Cypress |
07:10 pm - 09:30 pm | Opening Reception | Upper Pool Deck |
07:30 am - 04:30 pm | Registration | Registration Area 4 |
08:00 am - 08:15 am | Opening Remarks: Symposium Co-Chairs: Ved Srivastava, GlaxoSmithKline Andrei Yudin, University of Toronto |
Grand Cypress |
08:15 am - 09:55 am | SESSION I: SYNTHETIC METHODS Session Co-Chairs: Juan Del Valle, Moffitt Cancer Center John Vederas, University of Alberta |
Grand Cypress |
08:15 am - 08:40 am | L02 Masayuki Inoue, University of Tokyo Total Synthesis, Functional Analysis and Biological Evaluation of Antibiotic Peptide Natural Products |
Grand Cypress |
08:40 am - 08:55 am | L03 Xuechen Li, University of Hong Kong Ser/Thr Ligation-mediated Peptide Cyclization for Cyclic Peptide Synthesis; Total Synthesis and Medicinal Chemistry of Daptomycin |
Grand Cypress |
08:55 am - 09:15 am | L04 David Perrin, University of British Columbia Organotrifluoroborates for One-Step 18F-Labeling of Complex Peptides |
Grand Cypress |
09:15 am - 09:35 am | L05 Bradley Pentelute, Massachusetts Institute of Technology Cysteine Arylation Enables Production of Abiotic Peptides and Antibodies |
Grand Cypress |
09:35 am - 09:55 am | L06 Ludger Wessjohann, Leibniz Institute of Plant Biochemistry Multiple Multicomponent Reactions – The Fast Track to Macrocyclic, N-Alkylated, Architectural and Bioactive Peptides |
Grand Cypress |
09:55 am - 10:30 am | Coffee and Pastries | Exhibit & Poster Areas |
10:30 am - 12:10 pm | SESSION II: PROTEOMICS & EPIGENETICS Session Co-Chairs: Paul Alewood, University of Queensland James Tam, Nanyang Technological University |
Grand Cypress |
10:30 am - 10:55 am | L07 Tom Muir, Princeton University When Bugs Talk: Virulence Regulation in Staphylococci |
Grand Cypress |
10:55 am - 11:10 am | L08 YI: Cristina Clement, Albert Einstein College of Medicine Lymph-Carried Self-Peptidome Derives from a Variety of Processing Enzymes and Contribute to the Dendritic cells MHC II Peptidome |
Grand Cypress |
11:10 am - 11:30 am | L09 Marcey Waters, University of North Carolina at Chapel Hill Reading Histone Post-Translational Modifications by Nature and Design |
Grand Cypress |
11:30 am - 11:50 am | L10 Matthew Bogyo, Stanford University School of Medicine Small Molecule Protease Probes as Optical Contrast Agents for Imaging Cancer |
Grand Cypress |
11:50 am - 12:10 pm | L11 Cheryl Arrowsmith, University of Toronto Molecular Recognition of Histone Peptides by Chromatin Regulators and Chemical Probes to Antagonize their Interactions |
Grand Cypress |
12:15 pm - 01:45pm | Lunch - provided | Exhibitor and Poster Areas |
International Liason Meeting | Orchid | |
01:50 - 03:30 pm | SESSION III: PEPTIDE BIOMATERIALS Session Co-Chairs: Thomas Kodadek, The Scripps Research Institute Joel Schneider, National Cancer Institute |
Grand Cypress |
01:50 pm - 02:15 pm | L12 Samuel Stupp, Northwestern University Bioactive Peptide Amphiphiles and Peptide DNA Nanostructures for Regenerative Medicine |
Grand Cypress |
02:15 pm - 02:30 pm | L13 YI: Angelo Bella, National Physical Laboratory Filming Fibrillogenesis in Real-Time |
Grand Cypress |
02:30 pm - 02:50 pm | L14 John Tovar, Johns Hopkins University The Protein Electric: Engineering Energy Transport Through Nanostructures Derived From the Self-assembly of Pi-conjugated Oligopeptides |
Grand Cypress |
02:50 pm - 03:10 pm | L15 Rein Ulijn, University of Strathclyde Simple Peptides as Building Blocks for Adaptive Nanotechnology |
Grand Cypress |
03:10 pm - 03:30 pm | L16 D.W.P.M. Löwik, Radboud University Nijmegen Peptide Based Materials for Cell Growth and Sensing |
Grand Cypress |
01:50 pm - 03:30 pm | WORKSHOP: Peptide CMC & Regulatory Challenges Session Co-Chairs: Fernando Albericio, Institute for Research in Biomedicine Matteo Villain, Bachem |
Grand Cypress GH |
01:50 pm - 02:10 pm | WS01 Daniel Samson, Bachem Application of the DoE Concept for Peptide API Process Development at Bachem |
Grand Cypress GH |
02:10 pm - 02:30 pm | WS02 Richard Raz, The National Institute for Medical Research Extended Peptide Ligation Using a Novel Cysteine-free Auxiliary |
Grand Cypress GH |
02:30 pm - 02:50 pm | WS03 Anita Szajek, United States Pharmacopeia Key Quality Attributes for Synthetic Peptide APIs and Drug Products |
Grand Cypress GH |
02:50 pm - 03:10 pm | WS04 Larisa Wu, Federal Drug Administration Team-Based Integrated Quality Assessment of Peptide Drug Applications in Office of Pharmaceutical Quality |
Grand Cypress GH |
03:10 pm - 03:30 pm | Discussion Moderators: Larisa Wu and Anita Szajek |
Grand Cypress GH |
03:30 pm - 04:00 pm | Refreshment Break | Exhibit and Poster Areas |
04:00 pm - 04:05 pm | Introduction of Merrifield Lecturer: Robin Offord, Mintaka Foundation & President APS |
Magnolia |
04:05 pm - 04:50 pm | MERRIFIELD AWARD LECTURE L17 Horst Kessler, TU München Design, Structure and Dynamics of Small Molecules, Peptides and Proteins |
Grand Cypress |
05:00 pm - 07:00 pm | Poster Session I Refreshments served, even numbers defend |
Regency/Portico/Prefunction |
07:00 pm - 09:00 pm | Student Mixer | Upper Pool Deck |
08:00 pm - 09:30 pm | Merrifield Award Reception Tickets at Registration |
La Coquina |
07:30 am - 04:30 pm | Registration | Registration Area 4 |
08:15 am - 09:55 am | SESSION IV: BIOACTIVE PEPTIDES Session Co-Chairs: Tom Muir, Princeton University Peter Schiller, Clinical Research Institute of Montreal |
Grand Cypress |
08:15 am - 08:40 am | L18 Philip Dawson, The Scripps Research Institute Addressing Bottlenecks in Complex Peptide and Protein Synthesis |
Grand Cypress |
08:40 am - 08:55 am | L19 Danielle Guarracino, The College of New Jersey The Nature of Peptidomimetics: Synthetic Peptide Macrocycles as Potential Therapeutics and Artificial Peptide Helices |
Grand Cypress |
08:55 am - 09:15 am | L20 Margaret Brimble, University of Auckland Synthesis and Properties of Collagenous Peptides Site-Specifically Modified with Advanced Gl Endproducts (AGEs) |
Grand Cypress |
09:15 am - 09:35 am | L21 David Fairlie, University of Queensland Downsizing Proteins Without Losing Potency or Function |
Grand Cypress |
09:35 am - 09:55 am | L22 John McMurray, M.D. Anderson Cancer Center Small Molecule Phosphopeptide Mimetics Targeting STAT6: New Agents for Asthma Therapy |
Grand Cypress |
09:55 am - 10:30 am | Coffee and Pastries | Exhibit & Poster Areas |
10:30 am - 12:10 pm | SESSION V: PEPTIDE STRUCTURE & FUNCTION Session Co-Chairs: John Mayer, Indiana University Jane Salik, PolyPeptide Group |
Grand Cypress |
10:30 am - 10:55 am | L23 Ronald Raines, University of Wisconsin - Madison The Main-Chain Oxygen: Unappreciated Effects on Peptide and Protein Structure |
Grand Cypress |
10:55 am - 11:10 am | L24 YI: Michael Ferracane, University of Florida Opioid Ligand Binding to Opioid Receptors: Insight and Implications for Peptide Design |
Grand Cypress |
11:10 am - 11:30 am | L25 Neal Zondlo, University of Delaware Electronic and Stereoelectronic Effects in Proteins: Tunable Structural Control via C–H/π Interactions, via σ→σ* and n→π* Interactions, and via Phosphorylation and O-GlcNAcylation |
Grand Cypress |
11:30 am - 11:50 am | L26 Yechiel Shai, Weizmann Institute of Science Imitating HIV Strategy to Shut down the Immune Response: Novel Peptides for the Treatment of Autoimmune Diseases |
Grand Cypress |
11:50 am - 12:10 pm | L27 Roderich Süssmuth, Technical University of Berlin Peptide Antibiotics in Bacterial Host Pathogen Interactions – Structures, Syntheses, and Bioactivities |
Grand Cypress |
12:15 pm - 01:45pm | Lunch - provided | Exhibitor and Poster Areas |
01:50 pm - 03:40 pm | SESSION VI: MACROCYCLES Session Co-Chairs: Jane Aldrich, University of Kansas Pravin Kaumaya, The Ohio State University |
Grand Cypress |
01:50 pm - 02:15 pm | L28 Tomi Sawyer, Merck & Co., Inc. Macrocyclic Peptide Drug Discovery: Exploring Intracellular Protein-Protein Interaction Target Space |
Grand Cypress |
02:15 pm - 02:30 pm | L29 Conor Scully, University of Toronto Synthesis and Applications of Electrophilic Peptide Macrocycles |
Grand Cypress |
02:30 pm - 02:50 pm | L30 Allyn Londregan, Pfizer, Inc. A Convenient Synthesis of Macrocyclic Peptides with Favorable Physical Properties |
Grand Cypress |
02:50 pm - 03:10 pm | L31 Scott Lokey, University of California, Santa Cruz Passive Membrane Permeability in Cyclic Peptides Inspired by Natural Products |
Grand Cypress |
03:10 pm - 03:40 pm | L32 Luke Hunter, University of South Wales Backbone-Fluorinated Cyclic Peptides: Investigation of Cyclization Efficiency, Molecular Conformation, and Biological Activity |
Grand Cypress |
03:40 pm - 05:20 pm | SESSION VII: PEPTIDE CATALYSIS Session Co-Chairs: Charles Deber, University of Toronto Robert Hodges, University of Colorado Denver |
Grand Cypress |
03:40 pm - 03:45 pm | GOODMAN LECTURE Introduction of Goodman Lecturer Robert Hodges, University of Colorado Denver |
Grand Cypress |
03:45 pm - 04:05 pm | L33 George Barany, University of Minnesota Orthogonal Solid-Phase Peptide Synthesis |
Grand Cypress |
04:05 pm - 04:20 pm | L34 Zachary Ball, Rice University Development of Rhodium Metallopeptides for Precise Perturbation of Protein Structure and Function |
Grand Cypress |
04:20 pm - 04:40 pm | L35 Scott Miller, Yale University Searching for Selective Reactions on Complex Molecular Scaffolds with Peptide-Based Catalysts |
Grand Cypress |
04:40 pm - 05:00 pm | L36 Christian Schafmeister, Temple University Building Atomically Precise, Nanometer Scale Active Sites |
Grand Cypress |
05:00 pm - 05:20 pm | L37 Helma Wennemers, ETH Zurich Peptides as Catalysts for Stereoselective C-C Bond Formations |
Grand Cypress |
05:20 pm - 07:30 pm | Poster Session II Refreshments served, odd numbers defend |
Regency/Portico/Prefunction |
07:30 am - 12:30 pm | Registration | Registration Area 4 |
08:15 am - 09:55 am | SESSION VIII: PEPTIDE MEDICINAL CHEMISTRY Session Co-Chairs: Kit Lam, University of California Davis Helma Wennemers, ETH Zurich |
Grand Cypress |
08:15 am - 08:20 am | DU VIGNEAUD LECTURE 1 Introduction of du Vigneaud Lecturer Ben Dunn, University of Florida |
Grand Cypress |
08:20 am - 08:40 am | L38 David Craik, University of Queensland Discovery of Cyclic Peptides in Plants and Their Applications in Drug Design and Agriculture |
Grand Cypress |
08:40 am - 08:55 am | L39 YI: Melody Fulton, University of Georgia Allosteric Inhibitors of the EGFR Asymmetric Dimer Interface |
Grand Cypress |
08:55 am - 09:15 am | L40 Justin Murray, Amgen Engineering Peptide Toxins for Ion Channel Targeting: Potent and Selective Antagonists of the Nav1.7 Sodium Channel from Tarantula Venom |
Grand Cypress |
09:15 am - 09:35 am | L41 James Tam, Nanyang Technological University Butelase 1: A Versatile and Multi-purpose Ligase |
Grand Cypress |
09:35 am - 09:55 am | L42 Mike Shipman, University of Warwick Oxetane Based Peptidomimetics: Potential New Tools for Drug Discovery and Chemical Biology |
Grand Cypress |
09:55 am - 10:30 am | Coffee and Pastries | Exhibit & Poster Areas |
10:30 am - 12:40 pm | SESSION IX: METABOLISM & SYNTHESIS of BIOACTIVE PEPTIDES Session Chair: David Farlie, University of Queensland Andrew Young, Phoundry Pharmaceuticals |
Grand Cypress |
10:30 am - 10:35 am | MAKINENI LECTURE Introduction of Makineni Lecturer Richard DiMarchi, Indiana University |
Grand Cypress |
10:35 am - 11:00 am | L43 Paramjit Arora, New York University Protein Domain Mimetics as Modulators of Protein-Protein Interactions |
Grand Cypress |
11:00 am - 11:20 am | L44 YI: Sylvia Els-Heindl, University of Leipzig High Metabolic in vivo Stability and Bioavailability of a Palmitoylated Ghrelin Receptor Ligand Assessed by Mass Spectrometry |
Grand Cypress |
11:20 am - 11:40 am | L45 Marco Kessler, Ironwood Pharmaceuticals Pharmacologic Properties, Metabolism, and Disposition of Linaclotide |
Grand Cypress |
11:40 am - 12:00 pm | L46 Mark Cancilla, Merck & Co., Inc. Characterizing the ADME Properties of Complex Therapeutic Peptides Using High Resolution Mass Spectrometry |
Grand Cypress |
12:00 pm - 12:20 pm | L47 Paul Alewood, University of Queensland Synthesis of Oxytocin Dendrimers that Maintain Potency and Structure and Inhibit Visceral Nociceptive Responses |
Grand Cypress |
12:20 pm - 12:40 pm | L78 Fa Liu, Calibrium, LLC Novel Synthetic Strategies for Insulin and Related Peptides |
Grand Cypress |
12:40 pm | Lunch - On Your Own | |
12:45 pm - 02:45 pm | Dr. Bert L. Schram Young Scientists' Lunch & Mixer Graduate Students & Post-docs only |
La Coquina |
12:45 pm - 02:00 pm | Biopolymers-Peptide Science Editorial Board Lunch & Meeting Editors and Editorial Advisory Board |
Orchid |
03:00 pm - 05:00 pm | WORKSHOP: Career Development: Job Search Strategy and Preparation Workshop Organizers: Jennifer Woods, Director - Human Resources, Ipsen Bioscience Natia Tsomaia, Assoociate Director - Compound Discovery, Ipsen Bioscience |
Grand Cypress GH |
03:00 pm - 04:00 pm | WS05 Interactive Talk: Stepping into Science and Owning your Career Building upon the experience of successful scientists in the field, we will provide guidelines and useful tips to help shape your carrier path. |
Grand Cypress GH |
04:00 pm - 05:00 pm | WS06 Hands-On-Roundtable You will meet scientists face to face and have the opportunity to ask questions and receive feedback. If you would like our team to review your CV, please email it in MS Word format by June 5th to the following address: . We will review the submitted documents and provide specific comments and suggestions. |
Magnolia |
06:00 pm - 09:30 pm | APS Council Meeting | Magnolia |
07:30 am - 04:30 pm | Registration | Registration Area 4 |
08:15 am - 09:55 am | SESSION X: EMERGING PEPTIDE TECHNOLOGIES Session Co-Chairs: Hossain Saneii, aapptec Mike Shipman, University of Warwick |
Grand Cypress |
08:15 am - 08:20 am | DU VIGNEAUD LECTURE 2 Introduction of du Vigneaud Lecturer Philip Dawson, The Scripps Research Institute |
Grand Cypress |
08:20 am - 08:40 am | L48 Jean Chmielewski, Purdue University Targeting Intracellular Pathogenic Bacteria with Unnatural Proline-Rich Peptides: Coupling Antibacterial Activity with Macrophage Penetration |
Grand Cypress |
08:40 am - 08:55 am | L49 YI: Timothy Siegert, Tufts University Cyclic Peptides that Bind a Vesicle Trafficking Protein: A Concerted Computational and Synthetic Approach |
Grand Cypress |
08:55 am - 09:15 am | L50 Michael Haller, Glytech Improving Peptide Drug Properties by Chemical Glycosylation |
Grand Cypress |
09:15 am - 09:35 am | L51 Ratmir Derda, University of Alberta Genetically-Encoded Libraries of Chemically-Modified Peptides |
Grand Cypress |
09:35 am - 09:55 am | L52 John Vederas, University of Alberta Structures, Syntheses and Functions of Antimicrobial Peptides from Gram Positive Bacteria |
Grand Cypress |
09:55 am - 10:30 am | Coffee and Pastries | Exhibit & Poster Areas |
10:30 am - 12:10 pm | SESSION XI: CELL PENETRATING PEPTIDES Session Co-Chairs: Ratmir Derda, University of Alberta Eileen Kennedy, University of Georgia |
Grand Cypress |
10:30 am - 10:55 am | L53 Bruce Maryanoff, The Scripps Research Institute Novel Peptide Molecules as Anti-Atherosclerosis Agents |
Grand Cypress |
10:55 am - 11:10 am | L54 YI: Punit Upadhyaya, The Ohio State University Direct Inhibition of Ras by Cell-permeable Cyclic Peptides |
Grand Cypress |
11:10 am - 11:30 am | L55 Paul Watt, CSO Phylogica Ltd Phylomer Derived Cell penetrating Peptides Facilitate More Efficient Delivery of Peptides and Proteins to the Cytoplasm |
Grand Cypress |
11:30 am - 11:50 am | L56 Shao Yao, National University of Singapore Recent Advances in Peptide and Small Molecule Microarray Applications |
Grand Cypress |
11:50 am - 12:05 pm | L57 YI: Abrrey Monreal, Washington State University SialoPen Peptides are New Cationic Foldamers with Excellent Permeability to HeLa and Primary Neuronal Cells |
Grand Cypress |
12:05 pm - 12:15 pm | Annoucement of the 25th American Peptide Symposium | Grand Cypress |
12:15 pm - 01:45pm | Lunch - provided | Exhibitor and Poster Areas |
12:15 pm - 01:45pm | Vincent du Vigneaud Award Lunch Reception Sponsored by Bachem By Invitation Only |
La Coquina |
01:30 pm - 03:30 pm | Poster Judging – Finalists (attended) | Regency/Portico/Prefunction |
03:40 pm - 05:20 pm | SESSION XII: IMMUNOTHERAPY Session Co-Chairs: Paramjit Arora, New York University Natia Tsomaia, Ipsen Bioscience, Inc. |
Grand Cypress |
03:40 pm - 04:05 | L58 Pravin Kaumaya, The Ohio State University A Paradigm Shift: Cancer Therapy with Peptide-Based B-Cell Epitope and Peptide Immunotherapeutics: Emerging Concepts and Validation of Combination Immunotherapy |
Grand Cypress DEF |
04:05 pm - 04:20 pm | L59 Jonathan Lai, Albert Einstein College of Medicine Peptides from pH-Dependent Viral Fusion Proteins: Structure, Function, and Inhibition of Cell Entry |
Grand Cypress DEF |
04:20 pm - 04:40 pm | L60 Bradley Nilsson, University of Rochester Rippled β-Sheet Fibrils from Coassembled Enantiomeric Amphipathic Peptides |
Grand Cypress DEF |
04:40 pm - 05:00 pm | L61 Keith Knutson, Mayo Clinic Jacksonville Vaccines for Prevention of Breast Cancer |
Grand Cypress DEF |
05:00 pm - 05:20 pm | L62 Thomas Kieber-Emmons, University of Arkansas Developing a First in Man Carbohydrate Mimetic Peptide Vaccine for Cancer: A Translational Story |
Grand Cypress DEF |
06:30 pm - 08:00 pm | Meet the Speakers | Grand Cypress GHI |
07:30 am - 10:30 am | Registration | Registration Area 4 |
08:15 am - 09:55 am | SESSION XIII: PEPTIDE THERAPEUTICS Session Co-Chairs: Carrie Haskel-Luevano, University of Florida Shao Yao, National University of Singapore |
Grand Cypress |
08:15 am - 08:40 am | L63 Richard Houghten, Torrey Pines Institute for Molecular Studies Accelerating Basic Research and Drug Discovery - from Hundreds of Compounds to Trillions! |
Grand Cypress |
08:40 am - 08:55 am | L64 YI: Emel Adaligil, Tufts University Discovery of D-Peptide Antibiotics Using Mirror-Image Phage Display |
Grand Cypress |
08:55 am - 09:15 am | L65 Yuji Kobayashi, Osaka University X-ray Crystallographic Analysis on the Complex between Collagen-Model Peptide and Pigment Epithelium-Derived Factor, PEDF |
Grand Cypress |
09:15 am - 09:35 am | L66 Tamis Darbre, University of Bern Potent Antimicrobial Peptide Dendrimers against Multi-Drug Resistant Pseudomonas aeruginosa |
Grand Cypress |
09:35 am - 09:55 am | L67 William Lubell, University of Montreal Examination of Azasulfurylpeptide Modulators of CD36 Towards a Treatment for Age-Related Macular Degeneration |
Grand Cypress |
09:55 am - 10:30 am | Coffee and Pastries | Grand Cypress Prefunction |
10:30 am - 12:10 pm | SESSION XIV: SESSION XIV: PEPTIDES IN THE CLINIC AND NEW TECHNOLOGIES Session Co-Chairs: Jung-Mo Ahn, University of Texas at Dallas Robert Hammer, Ra Pharmaceuticals |
Grand Cypress |
10:30 am - 10:55 am | L68 Claudio Schteingart, Ferring Research Institute Discovery and First Clinical Experience with Selepressin, a Selective hV1a Agonist for the Treatment of Hypotension in Septic Shock |
Grand Cypress |
10:55 am - 11:10 am | L69 Paul Feldman, GlaxoSmithKline Enteroendocrine Peptide Drug Discovery for Treatment of Metabolic Diseases |
Grand Cypress |
11:10 am - 11:30 am | L70 Kunwar Shailubhai, Synergy Pharmaceuticals Agonists of Guanylate Cyclase-C as Innovative Oral Drugs for Treatment of Gastrointestinal Disorders and Diseases |
Grand Cypress |
11:30 am - 11:50 am | L71 Gary Hattersley, Radius Health, Inc. Abaloparatide, an Optimized Bone Anabolic Peptide |
Grand Cypress |
11:50 am - 12:10 pm | L72 Tom Kodadek, The Scripps Research Institute Synthesis and Screening of Large, DNA-Encoded One Bead One Compound Libraries |
Grand Cypress |
12:10 pm - 01:40 pm | Lunch - on your own | |
01:40 pm - 03:10 pm | SESSION XV: PEPTIDE FORMATION & DELIVERY Session Co-Chairs: Maria Bednarek, Medlmmune Lte Waleed Danho, DANHO Associates, Inc. |
Grand Cypress |
01:50 pm - 02:15 pm | L73 Victor Hruby, University of Arizona Design of Multivalent Ligands That Cross the Blood Brain Barrier for the Treatment of Prolonged and Neuropathic Pain Without Toxicities |
Grand Cypress |
02:15 pm - 02:30 pm | L74 Ashtosh Chilkoti, Duke University Biomedical Applications of Stimulus Responsive Peptide Polymers |
Grand Cypress |
02:30 pm - 02:50 pm | L75 Andrea Leone-Bay, MannKind Corporation Oral Inhalation – A Simple Approach to Biologics Delivery |
Grand Cypress |
02:50 pm - 03:10 pm | L76 Peter Daddona, Zosano Pharma Corporation Stable Glucagon-Coated Microneedle Patch for Rapid Hypoglycemic Treatment-Formulation and Phase 1 Data |
Grand Cypress |
03:10 pm - 04:00 pm | CLOSING LECTURE Introduction of Closing Lecturer Ved Srivastava, GlaxoSmithKline, APS Co-Chair L77 Jeffrey Friedman, Rockefeller University Leptin Physiology, Pathophysiology and the Regulation of Glucose Metabolism |
Grand Cypress |
04:00 pm - 04:10 pm | Closing Remarks Philip Dawson, President, APS |
Grand Cypress |
06:30 pm - 10:00 pm | Closing Banquet Dinner, Dancing, Poster Awards |
Grand Cypress |